Characteristics of antibiotic resistant strains of Vibrio cholerae carrying SXT type integrative conjugative elements
نویسندگان
چکیده
منابع مشابه
Acquisition and Evolution of SXT-R391 Integrative Conjugative Elements in the Seventh-Pandemic Vibrio cholerae Lineage
UNLABELLED SXT-R391 Integrative conjugative elements (ICEs) are self-transmissible mobile genetic elements able to confer multidrug resistance and other adaptive features to bacterial hosts, including Vibrio cholerae, the causative agent of cholera. ICEs are arranged in a mosaic genetic structure composed of a conserved backbone interspersed with variable DNA clusters located in conserved hot s...
متن کاملPrevalence of SXT/R391-like integrative and conjugative elements carrying blaCMY-2 in Proteus mirabilis.
OBJECTIVES To characterize the vectors involved in the dissemination of bla(CMY-2) genes in clinical isolates of Proteus mirabilis collected between 1999 and 2007. METHODS Plasmid analysis of 19 P. mirabilis carrying ampC genes was performed by PCR-based replicon typing, S1-PFGE and Southern hybridization with ampC and replicon probes. Isolates that could not be characterized were examined fo...
متن کاملVariations in SXT elements in epidemic Vibrio cholerae O1 El Tor strains in China
Vibrio cholerae O1 El Tor biotype strains are responsible for three multiyear epidemics of cholera in China during the seventh ongoing pandemic. The presence of the integrative conjugative element SXT is strongly correlated with resistance to nalidixic acid, tetracycline, and trimethoprim-sulfamethoxazole in these strains. Here, we sequenced the conserved genes of the SXT element, including eex...
متن کاملVibrio cholerae SXT Element, Laos
To the Editor: The SXT element is a Vibrio cholerae–derived ICE (integrating and conjugative element), which has also been referred to as a conjugative transposon (1) or a constin (2). ICEs excise from the chromosomes of their hosts, transfer to a new host through conjugation, and then integrate into the chromosome again. SXT element was originally isolated in 1993 from a V. cholerae O139 clini...
متن کاملThe extended regulatory networks of SXT/R391 integrative and conjugative elements and IncA/C conjugative plasmids
Nowadays, healthcare systems are challenged by a major worldwide drug resistance crisis caused by the massive and rapid dissemination of antibiotic resistance genes and associated emergence of multidrug resistant pathogenic bacteria, in both clinical and environmental settings. Conjugation is the main driving force of gene transfer among microorganisms. This mechanism of horizontal gene transfe...
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ژورنال
عنوان ژورنال: Epidemiology and Infectious Diseases
سال: 2014
ISSN: 2411-3026,1560-9529
DOI: 10.17816/eid40820